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Cancer and Liver DiseaseHealth Professionals Blog

Treatment of undifferentiated embryonal sarcoma of the liver in children

Title: Treatment of undifferentiated embryonal sarcoma of the liver in children

Source: Cancers 2024, 16 (5): 897

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Date of publication: February 2024

Publication type: Review article

Abstract: Undifferentiated embryonal sarcoma of the liver is a rare mesenchymal tumor with a highly malignant potential. It occurs almost exclusively in the pediatric population and typically has a poor outcome. Although previous studies have reported dismal prognoses, recent advances in combined treatment modalities, e.g., surgery and chemotherapy, have given cause for optimism. Even in those diseases not amenable to complete surgical resection or refractory diseases, other treatment modalities, such as liver transplant, have yielded promising results. This paper provides a review of the current treatment modalities for hepatic undifferentiated embryonal sarcoma in children.

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